The conference is intended to explore the interaction between economic incentives, institutional features, and epistemic aspirations of science. It brings together economics, sociology, and philosophy of science and seeks to investigate, in particular, the interrelatedness between the social conditions under which science operates and the nature and content of the knowledge produced. Two major topical areas are addressed. First, the incentive structure in the scientific community and its impact on the research process. Second the influence of social and ecnonomic demands, as imposed on research, on the research outcome. The innovative character of the conference consists in tracing this interrelation between the social framework, for one, and the cognitive content of the knowledge gained and the procedures of confirmation invoked, for another.