Department of Chemistry
 
 
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Universität Bielefeld > Department of Chemistry
  

Research profile of the Faculty of Chemistry

  1. Molecule-based Materials
    Aziz-Lange, Ghadwal, Glaser, Godt, Hellweg, Hoge, Kohse-Höinghaus, Kühnle, Mitzel
  2. Life Science Chemistry
    Dierks, Fischer v. Mollard, Gröger, Hellweg, Kottke, Lübke, Niemann, Sewald
  3. Gas Phase- und Atmospheric Chemistry
    Brockhinke, Eisfeld, Kohse-Höinghaus, Koop, Manthe, Mitzel
  4. Public Understanding of Science
    Dunker, Kohse-Höinghaus, Lück, Mitzel

Important subjects in the research area Molecule-based Materials are molecular magnets, biomimetic catalysts, cytostatic compounds, fluorinated compounds, organometallic compounds, silanes, spin probes an models for EPR-spectroscopy, microgels and microemulsions.

Protein crystallography is used and sulfatases, lysosomal hydrolases and membrane transport are studied in the research area Life Science Chemistry. An additional focus are bioorganic and biocatalytic topics in organic chemistry groups, which are also investigated by biochemistry groups within the Faculty of Chemistry.

Research topics in Gas Phase- und Atmospheric Chemistry are combustion, atmospheric aerosols and ice nucleation. The core facility „gas-electron diffraction and structure analysis of small molecules“ (GED@BI, N. Mitzel) is funded by the DFG and is unique within the EU.

The research area Public Understanding of Science focuses on research concerning instructions in chemistry during early childhood.

The Faculty of Chemistry is characterized by interdisciplinary research, which is typical for Bielefeld University. Researchers in the research area Molecule-based Materials cooperate with the department of Physics.

The research area Life Science Chemistry is strengthened by cooperation with the Faculty of Biology, the Faculty of Technology and the CeBiTec.
The „Center for Molecular Materials“ CM2 is an academic department with groups from chemistry and physics (coordinator B.Hoge), which aims at connections between technical know-how of industrial partners and basic research at the university.
In addition, each group is involved in national and international research cooperations.


Current work from our research groups 


47
Three-Fold Scholl-Type Cycloheptatriene Ring Formation around a Tribenzotriquinacene Core: Toward Warped Graphenes
An unprecedented 3-fold Scholl-type cycloheptatriene ring formation around a tribenzotriquinacene core is realized, producing a polyaromatic arene with a wizard hat-shaped structure. The presence of three 3,4-dimethoxyphenyl rings at the C-1, C-4 and C-8 positions of the tribenzotriquinacene skeleton is crucial to the success of this transformation.
H.-W. Ip, C.-F. Ng, H.-F. Chow and D. Kuck, J. Am. Chem. Soc. 2016, 138, 13778–13781. [DOI: 10.1021/jacs.6b05820]



16
Molekulare Basis der Multiplen Sulfatasedefizienz (MSD), einer fatalen Erbkrankheit: Sulfatasen enthalten Formylglycin, eine neuartige Aminosäure, die durch das Formylglycin-generierende Enzym (FGE) post-translational aus Cystein hergestellt wird. Die 3D-Struktur des FGE wurde in der AG Dierks (BCI) in Koorperation mit Dr. Markus Rudolph (Strukturbiologie Göttingen) aufgeklärt und ist hier als Bänderdiagramm in grau dargestellt. Krankheitsverursachende Mutationen, die bislang in MSD-Patienten gefunden wurden, sind als farbige Kugeln hervorgehoben. Die Farbe gibt an, ob die jeweilige Mutation zur Destabilisierung der Struktur (rosa), zur Hemmung der Sulfatase-Bindung (blau) oder zur Blockierung der Enzymaktivität (türkis) führen. [Dierks et al. (2005) Cell 121, 541-552] [mehr ..]


Alle GDCh-Vorträge

663. Wilhelm and Else Heraeus-Seminar
CdCC 2017
Dynamics and Structure Formation of Organic Molecules on Dielectric Surfaces

25.02.2018

CM2


Magicbullet European Training Network MAGICBULLET


Core Facility



FOR 945

Nanomagnete: von der Synthese über die Wechselwirkung mit Oberflächen zur Funktion