Personal data:

Name: Dr. Lutz Wobbe
Telephone: +49 (0)521-106-12257
Fax: +49 (0)521-106-12290
e-mail: lutz.wobbe@uni-bielefeld.de

Diploma (06/2003)

Das Integrin α5β1: Eine neue Reinigungsstrategie mittels Affinitätschromatographie an immobilisierten Peptiden und ELISA-basierte Bindungsstudien

PhD studies (10/2003-07/2007)

Der cytosolische Translationsrepressor NAB1 in der einzelligen Grünalge C. reinhardtii

Post-Doc (08/2007-today)

(08/2007-08/2008) Postdoctoral fellow in the Alga Biotechnology Group at the University of Bielefeld
(08/2008-today) DFG research fellow: (10/2008-01/2010) Visiting researcher in the group of Prof. Peter Nixon at the Imperial College in London (UK)

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• Schönfeld, C., Wobbe, L., Borgstädt, R., Kienast, A., Nixon, P.J.  Kruse, O. (2004) The nucleus-encoded protein MOC1 is essential for mitochondrial light acclimation in Chlamydomonas reinhardtii. J. Biol. Chem. 279: 50366-50374
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• Zimmermann, D., Malesevic, M., Sewald, K., Guthoehrlein, E.W., Wobbe, L., Heggemann, C. & Sewald, N. (2005) Integrin α5β1 antagonists: biological evaluation using cell adhesion assay and surface plasmon resonance. ChemBioChem. 6: 272–276
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• Mussgnug, J.H., Wobbe, L., Elles, I., Claus, C., Hamilton, M., Fink, A., Kapazoglou, A., Mullineaux, C.W., Hippler, M., Nickelsen, J., Nixon, P.J. & Kruse, O. (2005) Nab1, an RNA-binding protein involved in the light-regulated differential expression of the light-harvesting antenna of Chlamydomonas reinhardtii. Plant Cell 17: 3409-3421
• Wobbe, L., Zimmermann, D., Wißbrock, M., Urman, S., Sewald, K., Malesevic, M. & Sewald, N. (2006) Integrin α5β1: a new purification strategy based on immobilized peptides. J. Peptide Res. 66: 22–29
• Wobbe, L., Schwarz, C, Nickelsen, J.& Kruse, O. (2008) Translational control of photosynthetic gene expression in phototrophic eukaryotes. Physiol. Plant. 133: 507-515
• Beckmann, J., Lehr, F., Finazzi, G., Hankamer, B., Posten, C., Wobbe, L. & Kruse, O. (2009) Improvement of light to biomass conversion by de-regulation of light-harvesting protein translation in Chlamydomonas reinhardtii. J. Biotechnol. 142: 70-77
• Wobbe, L., Blifernez, O., Schwarz, C., Mussgnug, J.H., Nickelsen, J. & Kruse, O. (2009) Cysteine modification of a specific repressor protein controls the translational status of nucleus-encoded LHCII mRNAs in Chlamydomonas. Proc. Natl. Acad. Sci. USA 106: 13290-13295