Inside Cover: Functionalized Pentafluoroethylphosphanes

For nearly 30 years trifluoromethyl-substituted phosphanes were exclusively accessible by derivatization of the corresponding iodo compounds, which had to be synthesized in costly high-pressure reactions in low yields. In many systems the replacement of the CF3 group by the C2F5 homologue provides a considerable increase in stability. In their Full Paper, B. Hoge and colleagues show that the aminophosphane C2F5P(NEt2)2 is accessible on a 40 g scale employing LiC2F5. The product represents a valuable starting material for a variety of pentafluoroethylphosphanes C2F5PX2 (X=Br, H, F, OH).