Bielefeld University Department of Chemistry Physical and Biophysical Chemistry deutsch


Refereed Publications

  • Spexard, M., Thöing, C., Beel, B., Mittag, M., and Kottke, T.* (2014)
    "Response of the Sensory Animal-Like Cryptochrome aCRY to Blue and Red Light as Revealed by Infrared Difference Spectroscopy",
    Biochemistry 53, 1041-1050.
  • Juhas, M., von Zadow, A., Spexard, M., Schmidt, M., Kottke, T., and Büchel, C.* (2014)
    "A Novel Cryptochrome in the Diatom Phaeodactylum tricornutum Influences the Regulation of Light Harvesting Protein Levels",
    FEBS J. 281, 2299-2311.
  • Thöing, C., Pfeifer, A., Kakorin, S., and Kottke, T.* (2013)
    "Protonated triplet-excited flavin resolved by step-scan FTIR spectroscopy: Implications for photosensory LOV domains",
    Phys. Chem. Chem. Phys. 15, 5916-5926.
  • Herman, E., Sachse, M., Kroth, P. G., and Kottke, T.* (2013)
    "Blue-Light-Induced Unfolding of the Jα Helix Allows for the Dimerization of Aureochrome-LOV from the Diatom Phaeodactylum tricornutum",
    Biochemistry 52, 3094-3101.
  • Immeln, D., Weigel, A., Kottke, T.*, and Pérez Lustres, J. L.* (2012)
    "Primary Events in the Blue Light Sensor Plant Cryptochrome: Intraprotein Electron and Proton Transfer Revealed by Femtosecond Spectroscopy",
    J. Am. Chem. Soc. 134, 12536-12546.
  • Burney, S., Wenzel, R., Kottke, T., Roussel, T., Hoang, N., Bouly, J.-P., Bittl, R., Heberle, J., and Ahmad, M.* (2012)
    "Single Amino Acid Substitution Reveals Latent Photolyase Activity in Arabidopsis cry1",
    Angew. Chem. Int. Ed. 51, 9356-9360.
    Angew. Chem. 124, 9490-9494.
  • Beel, B. §, Prager, K. §, Spexard, M. §, Sasso, S., Weiss, D., Müller, N., Heinnickel, M., Dewez, D., Ikoma, D., Grossman, A. R., Kottke, T., and Mittag, M.* (2012)
    "A Flavin Binding Cryptochrome Photoreceptor Responds to Both Blue and Red Light in Chlamydomonas reinhardtii",
    Plant Cell 24, 2992-3008.
  • § contributed equally

  • Spexard, M., Immeln, D., Thöing, C., and Kottke, T.* (2011)
    "Infrared Spectrum and Absorption Coefficient of the Cofactor Flavin in Water",
    Vib. Spectrosc. 57, 282-287.
  • Bauer, C., Rabl, C.-R., Heberle, J., and Kottke, T.* (2011)
    "Indication for a Radical Intermediate Preceding the Signaling State in the LOV Domain Photocycle",
    Photochem. Photobiol. 87, 548-553.
  • Immeln, D., Pokorny, R., Herman, E., Moldt, J., Batschauer, A., and Kottke, T.* (2010)
    "Photoreaction of Plant and DASH Cryptochromes Probed by Infrared Spectroscopy: The Neutral Radical State of Flavoproteins",
    J. Phys. Chem. B 114, 17155-17161.
  • Kottke, T.*, van de Linde, S., Sauer, M., Kakorin, S., and Heilemann, M.* (2010)
    "Identification of the Product of Photoswitching of an Oxazine Fluorophore Using Fourier Transform Infrared Difference Spectroscopy",
    J. Phys. Chem. Lett. 1, 3156-3159.
  • Thamarath, S. S., Heberle, J., Hore, P. J., Kottke, T.*, and Matysik, J.* (2010)
    "Solid-State Photo-CIDNP Effect Observed in Phototropin LOV1-C57S by 13C Magic-Angle Spinning NMR Spectroscopy",
    J. Am. Chem. Soc. 132, 15542-15543.
  • Pfeifer, A., Mathes, T., Lu, Y., Hegemann, P., and Kottke, T.* (2010)
    "Blue Light Induces Global and Localized Conformational Changes in the Kinase Domain of Full-Length Phototropin",
    Biochemistry 49, 1024-1032.

    Selected by the Faculty of 1000 as one of the top 2% of published articles in biology and medicine (Liscum E: 2010. F1000.com/6083956)

  • Ataka, K., Kottke, T., and Heberle, J.* (2010)
    "Thinner, Smaller, Faster: IR Techniques To Probe the Functionality of Biological and Biomimetic Systems",
    Angew. Chem. Int. Ed. 49, 5416-5424.

    Ataka, K., Kottke, T., and Heberle, J.* (2010)
    "Dünner, kleiner, schneller - wie die IR-Spektroskopie zur Aufklärung des Funktionsmechanismus biologischer und biomimetischer Systeme beiträgt",
    Angew. Chem. 122, 5544-5553.

  • Langenbacher, T., Immeln, D., Dick, B., and Kottke, T.* (2009)
    "Microsecond Light-induced Proton Transfer to Flavin in the Blue Light Sensor Plant Cryptochrome",
    J. Am. Chem. Soc. 131, 14274-14280.
  • Maag, D., Kottke, T., Schulte, M., and Godt, A.* (2009)
    "Synthesis of Monodisperse Oligo(1,4-phenyleneethynylene-alt-1,4-triptycyleneethynylene)s",
    J. Org. Chem. 74, 7733-7742.
  • Bahlawane, N.*, Ngamou, P. H. T., Vannier, V., Kottke, T., Heberle, J., and Kohse-Höinghaus, K. (2009)
    "Tailoring the properties and the reactivity of the spinel cobalt oxide",
    Phys. Chem. Chem. Phys. 11, 9224-9232.
  • Pfeifer, A., Majerus, T., Zikihara, K., Matsuoka, D., Tokutomi, S., Heberle, J., and Kottke, T.* (2009)
    "Time-Resolved Fourier Transform Infrared Study on Photoadduct Formation and Secondary Structural Changes within the Phototropin LOV Domain",
    Biophys. J. 96, 1462-1470.
  • Immeln, D., Schlesinger, R., Heberle, J., and Kottke, T.* (2007)
    "Blue Light Induces Radical Formation and Autophosphorylation in the Light-sensitive Domain of Chlamydomonas Cryptochrome",
    J. Biol. Chem. 282, 21720-21728.
  • Majerus, T., Kottke, T., Laan, W., Hellingwerf, K., and Heberle, J.* (2007)
    "Time-resolved FT-IR spectroscopy traces signal relay within the blue-light receptor AppA",
    ChemPhysChem 8, 1787-1789.
  • Berndt, A., Kottke, T., Breitkreuz, H., Dvorsky, R., Hennig, S., Alexander, M., and Wolf, E.* (2007)
    "A Novel Photoreaction Mechanism for the Circadian Blue-Light Photoreceptor Drosophila Cryptochrome",
    J. Biol. Chem. 282, 13011-13021.
  • Kottke, T., Hegemann, P., Dick, B., and Heberle, J.* (2006)
    "The Photochemistry of the Light-, Oxygen-, and Voltage-Sensitive Domains in the Algal Blue Light Receptor Phot",
    Biopolymers 82, 373-378.
  • Kottke, T.*, Batschauer, A., Ahmad, M., and Heberle, J. (2006)
    "Blue-Light-Induced Changes in Arabidopsis Cryptochrome 1 Probed by FTIR Difference Spectroscopy",
    Biochemistry 45, 2472-2479.
  • Guo, H., Kottke, T., Hegemann, P., and Dick, B.* (2005)
    "The Phot LOV2 Domain and its Interaction with LOV1",
    Biophys. J. 89, 402-412.
  • Losi, A.*, Kottke, T., and Hegemann, P. (2004)
    "Recording of blue light-induced energy and volume changes within the wild-type and mutated phot-LOV1 domain from Chlamydomonas reinhardtii",
    Biophys. J. 86, 1051-1060.
  • Kottke, T.*, Dick, B., Fedorov, R., Schlichting, I., Deutzmann, R., and Hegemann, P. (2003)
    "Irreversible Photoreduction of Flavin in a Mutated Phot-LOV1 domain",
    Biochemistry 42, 9854-9862.
  • Kottke, T.*, Heberle, J., Hehn, D., Dick, B., and Hegemann, P. (2003)
    "Phot-LOV1: Photocycle of a Blue-Light Receptor Domain from the Green Alga Chlamydomonas reinhardtii",
    Biophys. J. 84, 1192-1201.
  • *corresponding author

Unrefereed Publications

  • Beel, B., Müller, N., Kottke, T., and Mittag, M. (2013)
    "News about cryptochrome photoreceptors in algae",
    Plant Sig. Behav. 8, 1-4.
  • Kottke, T. (2012)
    "An den Grenzen der Sensitivität der FT-IR-Spektroskopie: Die Dynamik von biologischen Blaulichtsensoren",
    Bunsen-Magazin 14, 38-43.
    > PDF <
  • Kottke, T. (2011)
    "Durch Infrarotspektroskopie von einem statischen zu einem dynamischen Bild der Photochemie von sensorischen Blaulichtrezeptoren",
    Habilitation treatise, Bielefeld University, Germany.
  • Pfeifer, A., and Kottke, T. (2011)
    "The big exception: flavin-blue-light sensors",
    Nachr. Chem. 59, 23-28.
    > PDF <
  • Kottke, T. (2003)
    "Spektroskopische Aufklärung des Photozyklus der LOV1-Domäne eines Phot-Blaulichtrezeptors",
    PhD thesis, University of Regensburg, Germany.

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