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Universität Bielefeld > Fakultät für Chemie > Organische Chemie III > Magicbullet > PhD Students
  

General Information

Barbara Korsak Barbara Korsak
21/09/1988
Polish


Scientific Education

since 10/2015

Early Stage Researcher/PhD candidate in the ETN Magicbullet at Heidelberg Pharma GmbH.
PhD topic: Small Molecule –α– amanitin conjugates for targeted cancer therapy.

09/2013 – 08/2015

Early Stage Researcher, Department of Chemistry University of Aveiro/Institute of Molecular Pathology and Immunology at the University of Porto.
Topic: Development and biological evaluation of IgG-photosensitizer conjugates for targeted photodynamic therapy of gastric cancer.

01/2012 – 05/2012

Erasmus LLP Fellowship, Department of Analytical and Physical Chemistry, Faculty of Pharmacy, University of Porto.
Topic: Assessment of ability of statins and endogenous compounds to prevent protein oxidation.

10/2007 – 03/2013

M. Pharm. at the Medical University of Warsaw.
Master thesis: Investigation of photodynamic therapy effect on the induction of grp78 gene promoter.

Publications

  • Firczuk M, Gabrysiak M, Barankiewicz J, Domagala A, Nowis D, Kujawa M, Jankowska-Steifer E, Wachowska M, Glodkowska-Mrowka E, Korsak B, Winiarska M, Golab J., GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy. CellDeath Dis, 2013. 4: p. e741. doi: 10.1038/cddis.2013.265
  • Pereira PM, Korsak B, Sarmento B, Schneider RJ, Fernandes R, Tomé JP., Antibodies armedwith photosensitizers: from chemical synthesis to photobiological applications. Org BiomolChem, 2015. 13(9): p. 2518-29. doi: 10.1039/c4ob02334j
  • Marques SS, Magalhães LM, Mota AI, Soares TR, Korsak B, Reis S, Segundo MA., Myoglobin microplate assay to evaluate prevention of protein peroxidation. J Pharm BiomedAnal, 2015. 114: p. 305-311. doi: 10.1016/j.jpba.2015.06.006
  • González-Delgado JA, Castro PM, Machado A, Araújo F, Rodrigues F, Korsak B, Ferreira M, Tomé JP, Sarmento B., Hydrogels containing porphyrin-loaded nanoparticles for topical photodynamic applications. Int J Pharm., 2016 Aug 20;510(1):221-31. doi: 10.1016/j.ijpharm.2016.06.037

Presentations

  • "Development and biological evaluation of photosensitizer-anti-HER2 conjugates for targeted photodynamic therapy of gastric cancer", Antibody/Targeted Drug Conjugates 2015 Conference, Porto, Portugal, 13-15.04.2015.
  • "Development and biological evaluation of third generation HER2 targeted photosensitizers for photodynamic therapy of gastric cancer", 16th Congress of the European Society for Photobiology, Aveiro, Portugal, 31.08-04.09.2015, P011.
  • "Synthesis and Biological Evaluation of Photosensitizers for Targeted Photodynamic Therapy of Gastric Cancer", XX Luso-Galego Chemistry Meeting, Porto, Portugal, 26-28.11.2014.