ZiF Research Group
Cognitive Behavior of Humans, Animals, and Machines:
Situation Model Perspectives
October 2019 – July 2020
Convenors: Werner Schneider (Bielefeld, GER), Helge Ritter (Bielefeld, GER)
Prof. Schäbitz studied medicine at the Universities Hamburg and Heidelberg (1989-1994). In 1995, he received his doctoral degree (MD) from the University of Heidelberg, where he was appointed thereafter and finished his habilitation in 2004. Since 2004, Prof. Schäbitz is a certified board specialist in neurological intensive care, is the chief of the Stroke and Neurointensive Care unit and the head of a stroke research group and since 2007 Professor at the Department of Neurology at the University of Münster. Since 2009, he is chief of neurology at the EvKB. He is member of national and international societies, speaker of press of the German Stroke Association, reviewer for the major stroke journals, senior editor of the journal Stroke, and received several honors including the award of the German Society of Neurology for cerebrovascular research (Adolf-Wallenberg-Preis). He participated in, designed and conducted several clinical multicenter stroke trials.
Current Main Research Interests
Basic research in focal cerebral ischemia led to major insights into stroke pathophysiology resulting in important translational breakthroughs building the basis of modern stroke diagnosis and therapy. Although this significantly improved diagnosis (Israel et al., 2017) and therapy in the acute phase, a specific treatment in the subacute and chronic phase of the disease is not available. Research focused therefore on better understanding of mechanisms of poststroke recovery and regeneration processes (Minnerup et al., 2018; Sommer & Schäbitz, 2017) as well as therapies to enhance brain repair (Mammele et al., 2016) and recovery of neurological function (Diederich et al., 2017). Recently, focus is directed to development of brain computer interfaces, its translation into the clinic including design of training paradigms for detection and improval of poststroke cognitive dysfunction including neglect and hemianopia.
Five selected publications with particular relevance to the Research Group
- Minnerup, J., Strecker, J. K., Wachsmuth, L., Hoppen, M., Schmidt, A., Hermann, D. M., Wiendl, H., Meuth, S., Faber, C., Diederich, K., & Schäbitz, W. R. (2018). Defining mechanisms of neural plasticity after brainstem ischemia in rats. Annals of Neurology, 83, 1003-1015.
- Diederich, K., Bastl, A., Wersching, H., Teuber, A., Strecker, J. K., Schmidt, A., Minnerup, J., & Schäbitz, W. R. (2017). Effects of different exercise strategies and intensities on memory performance and neurogenesis. Frontiers in Behavioral Neuroscience, 11, 47.
- Israel, C., Kitsiou, A., Kalyani, M., Deelawar, S., Ejangue, L. E., Rogalewski, A., Hagemeister, C., Minnerup, J., & Schäbitz, W. R. (2017). Detection of atrial fibrillation in patients with embolic stroke of undetermined source by prolonged monitoring with implantable loop recorders. Thrombosis and Haemostasis, 117, 1962-1969.
- Sommer, C. J., & Schäbitz, W. R. (2017). Fostering poststroke recovery: Towards combination treatments. Stroke, 48, 1112-1119.
- Mammele, S., Frauenknecht, K., Sevimli, S., Diederich, K., Bauer, H., Grimm, C., Minnerup, J., Schäbitz, & Sommer, C. J. (2016). Prevention of an increase in cortical ligand binding to AMPA receptors may represent a novel mechanism of endogenous brain protection by G-CSF after ischemic stroke. Restorative Neurology and Neuroscience, 34, 665-675.