The Faculty of Biology is highly research oriented. Research fields of our research groups cover a variety of innovative biological subjects.
We are seeking to understand how fishes navigate their environment using either electrical or hydrodynamical cues.
In our effort to unravel how perception of the aquatic environment is achieved and how sensory-motor interactions influence each other, we employ various techniques ranging from quantitative behavior to neurophysiological approaches, theoretical modeling and technical implementations.
We investigate the potential of microalgae for the utilization of light energy and CO2 for the biotechnological production of valuable compounds in fundamental and applied research projects.
Photosynthetic microalgae use light energy for growth and can exhibit comparably high biomass yields, therefore offering the potential for sustainable production of numerous renewable products. Targets in the focus of our current research include hydrocarbons, carbohydrates, lipids, recombinant proteins and other bioactive molecules.
We study animal behaviour within the framework of the four questions of Tinbergen, both in the lab and in the field.
Combining individual life histories with experiments, comparative approaches and population-level data, our research evaluates the fitness value of behaviour but also tries to understand the mechanisms by which behavioural variation evolves.
Our work group studies the distribution of meiobenthos and the diversity, taxonomy of nematodes as well as their feeding types.
We have pursued this long-standing interest through investigations of lakes, rivers and other types of aquatic habitats. We are interested in the interactions of the benthic food web, from bacteria to meiobenthos, macrobenthos, and young fish.
Ecotoxicology is another field of our work. The inflow of harmful substances into the environment has steadily risen over the past several decades. Our major are to assess the potential risk of these chemicals and to evaluate and define thresholds below which they impose no deleterious effects on the living environment.
The collection focusses on the mid-European fauna, but samples from other regions are available as well.
Besides the systematically structured collection for teaching and reference many fascinating and instructive exhibits may be found. In research we are interested in plant-pollinator interactions.
Our overall goal in science is to understand the mechanisms underlying the control of natural movement and action sequences.
To this end, we study the adaptive locomotion abilities of insects with a research focus on the function of active tactile sensing (touch) and distributed proprioception (the sense of posture). Methodologically, we combine approaches from behavioural physiology (e.g., motion capture), electrophysiology (e.g., intracellular recordings) and biomimetic modeling in software and hardware.
Our Department focusses on teacher training and professionalisation for different school types.
By involving university students in various project and laboratory courses (teutolab-biotechnologie, Kolumbus-Kids, Biologie hautnah, Experimentier AG), they are given the opportunity to practice working with pupils on a sound theoretical background and also to conduct didactical research.
In Biology Education (Didactics of Biology), we are concerned with the acquisition of scientific literacy including teaching and learning of the methods and contents of biology.
Our research focusses on self-regulated and self-determined learning, respectively, comprising learning processes within heterogeneous learning groups. Key aspects of our research and further research in our domain are continuously integrated into our teacher training to ensure a contemporary biology teacher education.
A major interest is a deep understanding of the function of the transcription factor NF-kB (nuclear factor 'kappa-light-chain-enhancer' of activated B-cells) in the nervous system, especially in neurons, glia and neural stem cells.
Currently, we are focusing our research on a new additional topic: isolation and characterisation of adult human neural crest-derived stem cells from various sources for the potential use in cell based therapies.
The major theme of our research is how single-cell organisms evolved into multicellular organisms with differentiated cells.
Using microalgae as model organisms, we search for key genes in development and explore the molecular requirements for multicellularity and cellular differentiation. We also study the molecular and cellular mechanisms that effect pattern formation and morphogenesis in multicellular organisms.
Another focus is on the molecular processes in light reception and phototaxis. Microalgae possess a sophisticated light-sensing system including photoreceptors and light-modulated signaling pathways to sense environmental information and secure the survival in a rapidly changing environment. Light-sensitive proteins from microalgae are used for the development of molecular tools in optogenetics.
In our group we explore the role of natural products that are involved in the communication between individuals within one or different species and which influence ecological interactions.
These natural products mediate interactions between plants, herbivorous insects and their antagonists (predators, parasitoids) as well as interactions between mutualistic partners such as fungi. We focus on the isolation and identification of such compounds and the elucidation of their functions in an ecological, behavioural, genetic, population-biological and evolutionary context.
Our mission is to understand the neurophysiological and computational principles underlying conscious perception and decision making.
We use an integrative approach by which we combine a number of experimental techniques to map brain activity at different spatiotemporal scales (e.g. neuroimaging, electrophysiology) with psychophysical and behavioural measures as well as advanced statistics and computational modelling.
Our group uses computer-based and lab-based methods to generate and analyze large datasets, such as transcriptomes, proteomes and metabolomes, and to construct metabolic and regulatory networks.
We focus on the analysis of acclimation and adaptation to adverse environmental conditions which influence plant productivity, especially the metabolic pathway of photosynthesis. We generate the datasets in the laboratory, analyze and visualize them with the help of computers and programming, and test the resulting hypotheses in the laboratory.
Our unifying theme is the study of behavioural traits important in pre- and post-copulatory sexual selection.
We study the evolution of these often sex-specific traits with a combination of theoretical and experimental approaches. For the empirical studies we conduct field and lab experiments, using insects, birds and flatworms as model species. Advanced statistical methods and analyses of literature data complement our research program, which strives to detect and test general concepts in behavioural ecology and evolutionary biology.
We study the mechanisms that control the activity of sets of genes which are together required to synthesize a specific bio-compound in plants.
The model system is the accumulation of pigments and colorants in Arabidopsis thaliana. Our research focusses on (i) transcription factor gene families, networks of transcription factors, (ii) structural and functional genomics of dicotyledonous crops, and (iii) on elucidating the function of genes that are initially only known as a DNA sequence in genomes.
We perform research in the field of molecular genetics and applied microbiology.
Our focus lies on (1) Characterization of global gene regulation and metabolic pathways, (2) Systems Biology on Corynebacterium glutamicum and Bacillus methanolicus as model organisms, (3) White Biotechnology with emphasis on rational strain development for the production of value-added chemicals.
We do research on visually guided orientation behaviour of insects.
We aim to understand the underlying computational mechanisms. Insects, such as flies or bumblebees, manage to solve complex spatial tasks: They avoid collisions with obstacles, and are able to detect appropriate landing sites and to approach them. We want to elucidate the computational principles, down to the level of neurons and neural networks that generate and control visually guided behaviour in complex cluttered environments.
Deregulation of cellular redox-homeostasis is a fundamental principle of reduced fitness, yield loss and disease development in all organisms.
Using up-to-date methods of proteomics, transcriptomics incl. translatome analysis, dynamic cell imaging, molecular biology and recombinant protein analyses, we aim to decipher the molecular and physiological mechanisms of damage development and efficient stress acclimation. To this end, we investigate e.g. high light acclimation, salinity and heat stress in Arabidopsis, sugar beet and rice, and pharmacological impact in plant and human cell models.
Genes, transcripts, proteins and metabolites are the physical building blocks of the cell.
The functional relations between these elements form a complex network of interactions that we call life. Our group intends to decode (tiny) parts of such networks to obtain a functional understanding of life processes.
RNA-based regulation emerges as a critical checkpoint in eukaryotic gene expression. Our international team focusses on the role of two major types of players, RNA-binding proteins and microRNAs.
We are interested in unravelling posttranscriptional networks controlled by ribonucleoproteins that are connected to circadian timekeeping and stress responses. Furthermore, we investigate molecular underpinnings of microRNA biogenesis and function.
Our research is focused on theoretical ecology and evolutionary biology, in particular on modelling interactions between ecological and evolutionary processes on various temporal and spatial scales.
Two of our main questions are: 1) How is genetic and phenotypic diversity maintained within and across species and what can genomic data tell us about these processes? 2) How do eco-evolutionary feedbacks influence whether a small population survives or goes extinct, especially under changing environmental conditions? To address these questions, we build stochastic and deterministic mathematical models and study them using analytic approaches, numerical methods, and computer simulations. Also, we are always interested in collaborating with empiricists to contrast our models with ecological and genetic data.