Our research group combines methods from organic chemistry, enzymology and directed evolution to design, evolve, apply and understand new enzyme function. We aim to develop biocatalysts for synthetic organic chemistry catalyzing fundamental C-C, C-N and C-O bond formations that do not have a good catalytic solution. These new enzymes will be applied in synthesis, increase our understanding in enzymology and can expand the metabolism in living organisms.
Gergel S, Soler J, Klein A, Schülke KH, Hauer B, Garcia-Borràs M, Hammer SC
ChemRxiv, 2023.
Gajdoš M, Wagner J, Ospina F, Köhler A, Engqvist MKM, Hammer SC
Angew. Chem. Int. Ed. 2023, 62, e202215093.
Ospina F, Schülke KH, Soler J, Klein A, Prosenc B, Garcia-Borràs M, Hammer SC
Angew. Chem. Int. Ed. 2022, 61, e202213056.
Selected as VIP paper by Angewandte Chemie.
Highlighted by B. List and M. Turberg in Synfacts 2023, 19, 0080.
Soler J, Gergel S, Klaus C, Hammer SC, Garcia-Borràs M
J. Am. Chem. Soc. 2022, 144, 15954-15968.
Klaus C, Hammer SC
Trends in Chemistry 2022, 4, 363-366.
Invited contribution to a focus issue on "Protein Engineering and Chemoenzymatic Synthesis".
Schülke KH, Ospina F, Hörnschemeyer K, Gergel S, Hammer SC
ChemBioChem, 2022, 23, e202100632.
Selected as VIP paper by ChemBioChem.
Highlighted in the ChemBioTalents 2022/23 collection.
Bengel LL, Aberle B, Egler-Kemmerer AN, Kienzle S, Hauer B, Hammer SC
Angew Chem Int Ed, 2021, 60, 5554-5560.
Selected as VIP paper by Angewandte Chemie.
Highlighted by B. List and J.L. Kennemur in Synfacts 2021, 17, 0322.
Hammer SC, Kubik G, Watkins E, Huang S, Minges H, Arnold FH
Science 2017, 358, 215-218.
Highlighted by S. Bormann in C&EN.
Highlighted by B. List and G.A. Shevchenko in Synfacts 2018, 14, 0083.
Highlighted by ACS in Chemistry Research of the year 2017.
PhD Student
Lucas is French and he studied organic chemistry in Marseille (France) and Trondheim (Norway). Lucas worked with Dr. Hervé Clavier and completed his master thesis with Prof. Elisabeth Jacobsen.
PhD Student
Matúš is from Bratislava (Slovakia) and studied biotechnology in Bratislava and Graz. Matúš joined our group after his master thesis with Prof. Robert Kourist.
PhD Student
Shubhanshu is from Madhya Pradesh (India) and studied chemistry at the Indian Institute of Technology (IIT) Bombay. Shubhanshu joined our group after his master thesis with Prof. Debabrata Maiti.
PhD Student
Cindy is from Switzerland where she studied chemical biology at ETH Zürich. Cindy joined us after her master thesis with Prof. Donald Hilvert.
Vanessa Reitz
PhD Student
Vanessa studied biology and biochemistry at the Philipps University of Marburg (Germany) and joined us after her master thesis with Dr. Johannes Rebelein at the Max Planck Institute of Terrestrial Microbiology.
PhD Student
Felipe comes from Colombia and is a chemist by training. Before joining our group, Felipe worked as lecturer and research assistant with Prof. Felipe Otálvaro at Universidad de Antioquia in Medellín.