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  • Allgemein- und Familienmedizin

    Campus der Universität Bielefeld
    Campus der Universität Bielefeld
    © fizkes/istock

LLKVP - S3 guideline on general practitioner risk counselling for cardiovascular prevention

Acronym: LLKVP

Study design: Systematic guidelines review

Duration: 01.01.2023 – 30.06.2024

Status: Ongoing

Ethics vote: n/a

Funding: Innovationsfonds des Gemeinsamen Bundesausschusses (Fördernummer 01VSF22012); no funding from the pharmaceutical industry or medical device manufacturers

Team location Bielefeld:

  • Project leader: Svetlana Puzhko, MD, PhD
  • Research assistants: Dr. Ana Isabel González González, Lara Schürmann


Cardiovascular disease (CVD) is the leading cause of death in Germany. In 2021, one third of all deaths were attributable to it. Primary prevention (i.e. preventing diseases before they develop) of CVD is therefore very important. The most important controllable risk factors for CVD include diabetes, high blood pressure, obesity, metabolic disorders and an unhealthy lifestyle (smoking, physical inactivity and an unhealthy diet). These risk factors can be influenced as part of primary prevention by changing habits, such as dietary changes or drug therapies, thereby reducing the risk of cardiovascular events such as heart attacks and strokes.

GP practices are particularly suitable for primary prevention. Due to the continuous care of patients, GPs can better assess the advantages and disadvantages associated with preventive measures. This enables them to help their patients make informed decisions and maintain successful prevention. In order to ensure that patients receive the best possible advice, GPs need guidelines for counselling. The guidelines should be based on the latest scientific evidence and take into account various socio-demographic and health characteristics.

© Copyright:

Research question:

What recommendations do national and international guidelines for the primary prevention of CVD in adults in GP care provide?Special consideration will be given to recommendations regarding different age groups, ethnicities and genders, as well as people with diabetes, multiple diseases and multi-medication.

Project description:

The aim of the project is to update the S3 guideline on risk counseling for cardiovascular prevention in general practice. Based on the results of a systematic review of existing guidelines topics for de novo research will be identified. All information will then be synthesized. Based on this evidence, a committee of representatives from various medical associations will formulate guideline recommendations for the prevention of cardiovascular disease. A practice advisory board made up of experienced general practitioners ensures the comprehensibility and practicability of the recommendations. Finally, the new version of the guidelines is published, as well as a short version of the guidelines, and a version for patients.

External partners:

  • Institut für Allgemeinmedizin, Philipps-Universität Marburg (Dr. Jörg Haasenritter, Dr. Veronika van der Wardt, Dr. Maren Bredehorst)
  • DEGAM authors group
  • Patient advisory panel
  • Representatives of Physicians Specialists Societies
  • Practice panel, consists of seven practicing general practitioners

Patient involvement:

A patient advisory board, consisting of four patients, is involved in the selection and prioritization of key questions, the creation of recommendations, and the formulation of patient information.

Data sharing guidelines:

After completion of the study, the data will be stored in the institutional repository of Bielefeld University PUB in accordance with the Bielefeld Resolutions on Open Access.

Keywords: Cardiovascular disease, Primary Prevention, Guideline, Counseling

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