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  • Prof. Dr. Gabriele Fischer von Mollard

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Prof. Dr. Gabriele Fischer von Mollard

Contact

Prof. Dr. Gabriele Fischer von Mollard

Telephone
+49 521 106-2081
Telephone secretary
+49 521 106-6918
Room
UHG F4-143
Prof. Dr. G. Fischer von Mollard

Complete List of Publications

 

Selected Publications

 

Heß, M. C., Bloess, S., Risse, J. M., Friehs, K., Fischer von Mollard, G. (2020). Recombinant expression of an L-amino acid oxidase from the fungus Hebeloma cylindrosporum in Pichia pastoris including fermentation. MicrobiologyOpen. 9:e1112. https://doi.org/10.1002/mbo3.1112

Bloess, S., Beuel, T., Krüger, T., Sewald, N., Dierks, T., Fischer von Mollard, G. (2019) Expression, characterization and site-specific covalent immobilization of an L-amino acid oxidase from the fungus Hebeloma cylindrosporum. Appl. Microbiol. Biotechnol. https://doi.org/10.1007/s00253-018-09609-7

Emperador-Melero, J., Huson, V., van Weering, J., Bollmann, C., ,Fischer von Mollard, G., Toonen, R.F., Verhage, M. (2018) Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi. Nat. Commun 9, 3421

Hahn, K., Neumeister, K., Mix, A., Kottke, T. Gröger, H., Fischer von Mollard, G. (2017) Recombinant expression and characterization of a L-amino acid oxidase from the fungus Rhizoctonia solani. Appl. Microbiol. Biotechnol. 101, 2853-2864

Jany, T., Moreth, A., Gruschka, C., Sischka, A., Spiering, A., Dieding, M., Wang, Y., Samo, SH., Stammler, A., Bögge, H., Fischer von Mollard, G., Anselmetti, D., Glaser, T. (2015) Rational design of a cytotoxic dinuclear Cu2 complex that binds by molecular recognition at two neighboring phosphates of the DNA backbone. Inorg. Chem. 54, 2679-2790

Walter, AM., Kurps, J., de Wit, H., Schöning, S., Toft - Bertelsen, TL., Lauks, J., Ziomkiewicz, I., Weiss, AN., Schulz, A., Fischer von Mollard, G., Verhage, M., Sørensen, JB. (2014) The SNARE protein vti1a functions in dense - core vesicle biogenesis. EMBO J. 33, 1681-1697

Gossing, M., Chidambaram, S., Fischer von Mollard, G. (2013) Importance of the N-terminal domain of the Qb-SNARE Vti1p for different membrane transport steps in the yeast endosomal system. PLoS ONE 8, e66304, doi:10.1371/journal.pone.0066304

Lórenz-Fonfría, VA., Resler, T., Krause, N., Nack, M., Gossing, M., Fischer von Mollard, G., Bamann, C., Bamberg, E., Schlesinger, R., Heberle, J. (2013) Transient protonation changes in channelrhodopsin-2 and their relevance to channel gating Proc. Natl. Acad. Sci. USA Plus E1273-E1281 (doi/10.1073/pnas.1219502110)

Wang, J., Gossing, M., Fang, P., Zimmermann, J., Li, X., Fischer von Mollard, G.*, Niu, L.*, Teng, M.* (2011) ENTH domains bind on opposite sides of two SNAREs. Proc. Natl. Acad. Sci. USA doi/10.1073/pnas.1013101108 *corresponding authors

Kunwar, AJ., Rickmann, M., Backofen, B., Browski, SM., Rosenbusch, J., Schöning, S., Fleischmann, T., Krieglstein, K., Fischer von Mollard, G. (2011) Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development. Proc Nat Acad Sci USA 108, 2575-2580

Dressel, R., Elsner, L., Novota, P., Kanwar, N., Fischer von Mollard, G. (2010) The exocytosis of lytic granules is impaired in Vti1b or Vamp8-deficient CTL leading to a reduced cytotoxic activity following antigen-specific activation. J. Immunol. 185, 1005-1014

Zimmermann, J., Chidambaram, S., Fischer von Mollard, G. (2010) Dissecting Ent3p: The ENTH domain binds different SNAREs via distinct amino acid residues while the C-terminus is sufficient for retrograde transport from endosomes. Biochem. J. 431, 123-134

Stein, I.S. *, Gottfried, A. *, Zimmermann, J., Fischer von Mollard, G. (2009) TVP23 interacts genetically with the yeast SNARE VTI1 and functions in retrograde transport from the early endosome to the late Golgi. Biochem. J. 419, 229-236

Chidambaram S., Zimmermann J., Fischer von Mollard, G. (2008) ENTH domain proteins are cargo adaptors for multiple SNARE proteins at the TGN endosome. J. Cell Sci. 121, 329-338

Dilcher, M., Veith, B., Chidambaram, S., Hartmann, E., Schmitt, HD., Fischer von Mollard, G. (2003) Use1p is a yeast SNARE protein required for retrograde traffic to the ER. EMBO J. 22, 3664-3674

Atlashkin, V., Kreykenbohm, V., Eskelinen, E.L., Wenzel, D.; Fayyazi, A., Fischer von Mollard, G. (2003) Deletion of the SNARE vti1b in mice results in loss of a single SNARE partner, syntaxin 8. Mol. Cell. Biol., 23, 5198-5207

Antonin, W., Riedel, D., Fischer von Mollard, G. (2000) The SNARE Vti1a-b is localized to small synaptic vesicles and participates in a novel SNARE complex. J. Neuroscience 20, 5724-5732

Fischer von Mollard, G., Nothwehr, S.F., Stevens, T.H. (1997) The yeast v-SNARE Vti1p mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12p. J. Cell Biol. 137 1511-1524

Curriculum Vitae

University education: Biochemistry in Tübingen, München, Berlin

Diplom, Biochemistry, Freie Universität Berlin,1989

Dr. rer. nat., Freie Universität Berlin,1992

Diploma and dissertation with R. Jahn at the Max-Planck-Institut für Psychiatrie, München-Martinsried and at Yale University School of Medicine, New Haven, USA (since 8-1991) about rab proteins in synaptic vesicles

Postdoctoral fellow, University of Oregon, Eugene (USA) with T.H. Stevens 1994 – 1998 about SNAREs in yeast vacuolar traffic

Junior group leader, Universität Göttingen, Biochemistry II, 1998 – 2004 Nachwuchsgruppe: 'Homöostase des endosomalen Apparats in Säugerzellen' supported by Volkswagen Stiftung

Habilitation in Biochemistry, Universität Göttingen, 2002

Professor for Cell Biochemistry, Ruhr-Universität Bochum (2004)

Professor for Biochemistry III, Universität Bielefeld (2005)


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