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Aureliano Zana

Philochem AG, Switzerland - ESR 08
E-Mail: aureliano.zana@philochem.ch

Personal Information

Name Aureliano Zana
Date of Birth 04.05.1994
Nationality Italian

Scientific Education

since 06/2020

PhD student/Research associate
ETN Magicbullet::Reloaded
Philochem AG (Zurich)
Synthesis and biological evaluation of Small Molecule Drug Conjugates (SMDCs)

10/2019 – 03/2020

Research assistant (volunteer)
University of Milan – Department of Pharmaceutical Sciences (DISFARM)

09/2014 – 10/2019 Master thesis: Design, synthesis and biological evaluation of 3-bromo-isoxazoline covalent inhibitors of GAPDH as antimalarial agents
M.Sc. in Medicinal Chemistry
University of Milan (Italy)

Publications

  1. Covalent inhibitors of GAPDH: From unspecific warheads to selective compounds, Eur J Med Chem, 2020, 1;207:112740, doi: 10.1016/j.ejmech.2020.112740. [Link]

  2. Immunotherapy with Immunocytokines and PD-1 Blockade Enhances the Anticancer Activity of Small Molecule-Drug Conjugates Targeting Carbonic Anhydrase IX, Mol Cancer Ther, 2021, 20:512–22, doi: 10.1158/1535-7163.MCT-20-0361. [Link]


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