Biostatistik und Medizinische Biometrie
Team
Leitung
Prof. Dr. rer. nat. Annika Hoyer
Professur für Biostatistik und Medizinische Biometrie
- Telefon
- +49 521 106-86707
- Telefon Sekr.
- +49 521 106-86718
- Raum
- R.1 D3-100
- Publications (124)
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Pauly N, Birte S, Ulf T, et al. Assessing The HER2-Expression Landscape In Squamous Vulvar Cancer. Update Of The UK-OWL GO 1 Vulvar Cancer Subgroup. In: International Journal of Gynecological Cancer. Vol 35. Elsevier BV; 2025. (2025)
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Tönnies T, Voeltz D, Voß S, Hoyer A, Brinks R. Future prevalence of type 2 diabetes in Germany: a projection until 2040 including incidence trends observed during the SARS-CoV-2 pandemic. Frontiers in Epidemiology . 2025;5: 1388189. (2025)
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Rodenkirchen J, Hoyer A, Brinks R. Modeling the temporal prevalence peak drift of chronic diseases. BMC Medical Research Methodology . 2025;25(1): 65. (2025)
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Gerards M, Miller J, Doshi D, Hoyer A, Flöttmann N, Barthlen W. Virtual reality for distraction during painful procedures in pediatric surgery: A randomized clinical trial. Journal of Pediatric Nursing. 2025;82:116-122. (2025)
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Voß S, Hoyer A, Brinks R. Maximum likelihood estimation of age-specific incidence rate from prevalence. PLOS One. 2025;20(5): e0321924. (2025)
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Voß S, Hoyer A, Landwehr S, Pavkov ME, Gregg E, Brinks R. Additional file 1 of Estimation of mortality rate ratios for chronic conditions with misclassification of disease status at death. figshare; 2024. (2024)
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Stoye F, Kuss O, Hoyer A. Increasing flexibility for the meta-analysis of full ROC curves – a copula approach. Presented at the 69th GMDS Annual Conference, Dresden. (2024)
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Dineva A, Kuss O, Hoyer A. A “Double Copula” Model for Semi-Competing Risks Data. Presented at the 69th GMDS Annual Conference, Dresden. (2024)
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Voeltz D, Baginski K, Hornberg C, Hoyer A. Trends in the incidence and mortality of early-onset cancer in Germany between 1999 and 2019. Presented at the 69th GMDS Annual Conference, Dresden. (2024)
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Luo H, Petrera A, Hauck SM, et al. Plasma proteomics of all-cause and cause-specific mortality in individuals with and without type 2 diabetes: Results from two population-based KORA cohorts. European Heart Journal. 2024;45(Suppl. 1): ehae6662634. (2024)
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- Projects (2)
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Statistische Methoden für die Meta-Analyse von ROC-Kurven
Status: laufend Time: Jun 2023 - May 2026 -
Methodisch-epidemiologische Forschung zur Beschreibung der Dynamik des Typ-2-Diabetes
Status: laufend Time: Dec 2021 - Dec 2025
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Administration
Charlene Baumann
Sekretariat AG Biostatistik und Medizinische Biometrie
charlene.baumann@uni-bielefeld.de
- Telefon
- +49 521 106-86718
- Raum
- R.1 D3-102
Wissenschaftliche Mitarbeitende
Dr. Sandra Landwehr
Wissenschaftliche Mitarbeiterin
sandra.landwehr@uni-bielefeld.de
- Telefon
- +49 521 106-86710
- Raum
- R.1 D3-102
- Publications (24)
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Voß S, Hoyer A, Landwehr S, Pavkov ME, Gregg E, Brinks R. Estimation of mortality rate ratios for chronic conditions with misclassification of disease status at death. BMC Medical Research Methodology . 2024;24(1): 2. (2024)
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Voß S, Hoyer A, Landwehr S, Pavkov ME, Gregg E, Brinks R. Additional file 1 of Estimation of mortality rate ratios for chronic conditions with misclassification of disease status at death. figshare; 2024. (2024)
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Beyersdorf F, Bauer T, Freemantle N, et al. Five-year outcome in 18 010 patients from the German Aortic Valve Registry . European Journal of Cardio-Thoracic Surgery. 2021;60(5):1139-1146. (2021)
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Fujita B, Schmidt T, Bleiziffer S, et al. Impact of new pacemaker implantation following surgical and transcatheter aortic valve replacement on 1-year outcome. European Journal of Cardio-Thoracic Surgery. 2020;57(1):151-159. (2020)
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Landwehr S, Brinks R, Hoyer A. The Age of Onset of Dementias. In: de Girolamo G, McGorry PD, Sartorius N, eds. Age of Onset of Mental Disorders. Etiopathogenetic and Treatment Implications. Cham: Springer International Publishing; 2019: 237-253. (2019)
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Werner N, Zahn R, Beckmann A, et al. Patients at Intermediate Surgical Risk Undergoing Isolated Interventional or Surgical Aortic Valve Implantation for Severe Symptomatic Aortic Valve Stenosis. Circulation. 2018;138(23):2611-2623. (2018)
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Ensminger S, Fujita B, Bauer T, et al. Rapid Deployment Versus Conventional Bioprosthetic Valve Replacement for Aortic Stenosis. Journal of the American College of Cardiology. 2018;71(13):1417-1428. (2018)
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Brinks R, Hoyer A, Landwehr S. Surveillance of the Incidence of Non-Communicable Diseases (NCDs) with Sparse Resources: A Simulation Study Using Data from a National Diabetes Registry, Denmark, 1995–2004. PLOS ONE. 2016;11(3): e0152046. (2016)
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Lange R, Beckmann A, Neumann T, et al. Quality of Life After Transcatheter Aortic Valve Replacement. JACC: Cardiovascular Interventions. 2016;9(24):2541-2554. (2016)
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Tamayo T, Rathmann W, Stahl-Pehe A, et al. No adverse effect of outdoor air pollution on HbA1c in children and young adults with type 1 diabetes. International Journal of Hygiene and Environmental Health. 2016;219(4-5):349-355. (2016)
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Dr. rer. nat. Jürgen Rodenkirchen
Wissenschaftlicher Mitarbeiter
juergen.rodenkirchen@uni-bielefeld.de
- Telefon
- +49 521 106-86808
- Telefon Sekr.
- +49 521 106-86718
- Raum
- R.1 D3-101
- Publications (2)
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Rodenkirchen J, Hoyer A, Brinks R. Modeling the temporal prevalence peak drift of chronic diseases. BMC Medical Research Methodology . 2025;25(1): 65. (2025)
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Lopez Lumbi S, Masciangelo L, Liebig-Gonglach M, et al. How to measure the general Environmental Health Literacy. European Journal of Public Health. 2024;34(Supplement_3): ckae144.1684. (2024)
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- Curriculum Vitae
- Aktuelle Forschungsthemen
Diskrete Wahlmodelle
Bei diskreten Wahlmodellen geht es darum die Auswahlwahrscheinlichkeiten einer endlichen Menge von Wahlmöglichkeiten zu modellieren. Klassische Anwendungsfälle beinhalten die Verkehrsmittelwahl, politische Wahlen, oder auch Produktwahlen.Im Speziellen beschäftige ich mich mit der Composite Marginal Likelihood (CML) Schätzung von sogenannten Probit Modellen. Bei der CML Schätzung werden anstelle der gemeinsamen Wahrscheinlichkeit aller Beobachtungen zu einer Person das Produkt der Wahrscheinlichkeiten von Paaren von Beobachtungen genutzt. Dies reduziert den notwendigen Rechenaufwand beträchtlich. Dies geschieht auf Kosten der statistischen Effizienz des Schätzers.
Mein Fokus liegt aktuell darin
1. graphische Diagnosetools für CML Schätzer zu entwickeln,
2. anhand der Gradientenbeiträge der Beobachtungspaare auf Zeitabhängigkeiten innerhalb des Modells zu testen,
3. durch Gewichtungsstrategien den Verlust an Effizienz zu verringern, und
4. den Schätzer durch Gewichtungsstrategien robuster gegenüber Misspezifikation zu machen.- Publications (3)
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Büscher S. Strength out of Weakness: Harnessing Information Gained from the Pair Structure of Composite Marginal Likelihood Estimation. Bielefeld: Universität Bielefeld; 2025. (2025)
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Büscher S, Bauer D. Weighting strategies for pairwise composite marginal likelihood estimation in case of unbalanced panels and unaccounted autoregressive structure of the errors. Transportation Research Part B: Methodological. 2024;181: 102890. (2024)
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Büscher S, Batram M, Bauer D. Using Motifs for Population Synthesis in Multi-agent Mobility Simulation Models. In: Steland A, Rafajlowicz E, Okhrin O, eds. Stochastic Models, Statistics and Their Applications. Springer Proceedings in Mathematics & Statistics. Vol 294. Cham: Springer; 2019: 335-350. (2019)
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Antoniya Dineva
Wissenschaftliche Mitarbeiterin
antoniya.dineva@uni-bielefeld.de
- Telefon
- +49 521 106-86723
- Telefon Sekr.
- +49 521 106-86718
- Raum
- R.1 D3-103
- Publications (3)
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Klingenberg M, Dineva A, Hoyer A, et al. Injection of Autologous Adipose Stromal Vascular Fraction in Combination with Autologous Conditioned Plasma for the Treatment of Advanced Knee Osteoarthritis Significantly Improves Clinical Symptoms. Journal of Clinical Medicine. 2024;13(11): 3031. (2024)
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Dineva A, Kuss O, Hoyer A. A “Double Copula” Model for Semi-Competing Risks Data. Presented at the 69th GMDS Annual Conference, Dresden. (2024)
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Dineva A, Kuß O, Hoyer A. A New Parametric Accelerated Failure Time Model for Semi-Competing Risk Data. (2023)
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Kira Baginski
Wissenschaftliche Mitarbeiterin
kira.baginski@uni-bielefeld.de
- Telefon
- +49 521 106-86807
- Raum
- R.1 D3-101
- Publications (4)
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Voeltz D, Baginski K, Hornberg C, Hoyer A. Trends in incidence and mortality of early-onset cancer in Germany between 1999 and 2019. European Journal of Epidemiology. 2024. (2024)
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Baginski K, Voeltz D, Hoyer A. Projected number of people with multiple sclerosis in Germany between 2015 and 2040. Multiple Sclerosis and Related Disorders. 2024;89: 105774. (2024)
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Voeltz D, Baginski K, Hornberg C, Hoyer A. Correction: Trends in incidence and mortality of early-onset cancer in Germany between 1999 and 2019. European Journal of Epidemiology. 2024. (2024)
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Voeltz D, Baginski K, Hornberg C, Hoyer A. Trends in the incidence and mortality of early-onset cancer in Germany between 1999 and 2019. Presented at the 69th GMDS Annual Conference, Dresden. (2024)
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Ferdinand Stoye
Wissenschaftlicher Mitarbeiter
ferdinand.stoye@uni-bielefeld.de
- Telefon
- +49 521 106-86732
- Raum
- R.1 D3-103
- Aktuelle Forschungsthemen
Methodenentwicklung für die Meta-Analyse von Diagnosestudien
- Publications (4)
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Meier C, Israel C, Eisenblätter M, et al. Safety of magnetic resonance imaging in patients with cardiac implantable electronic devices and abandoned or epicardial leads – a systematic review and meta-analysis. Europace. 2024. (2024)
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Stoye F, Tschammler C, Kuss O, Hoyer A. A discrete time-to-event model for the meta-analysis of full ROC curves. Research synthesis methods. 2024;15(6):1031-1048. (2024)
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Stoye F, Kuss O, Hoyer A. Increasing flexibility for the meta-analysis of full ROC curves – a copula approach. Presented at the 69th GMDS Annual Conference, Dresden. (2024)
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Stoye F, Langrock R. Autoregressive hidden Markov models for high-resolution animal movement data. In: Bergherr E, Groll A, Mayr A, eds. Proceedings of the 37th International Workshop on Statistical Modelling. Part II. 2023: 294-299. (2023)
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